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User's guide for the Gaussian type dispersion models CONCX and CONDEP. NILU TR
Rapporten inneholder en brukerbeskrivelse av de Gaussiske programmene CONCX og CONDEP, som beregner henholdsvis korttids- og langtidsverdier av konsentrasjoner for utslipp fra en eller flere skorsteiner. Rapporten inneholder en teoretisk del med bakgrunn for beregningene i tillegg til beregningseksempler.
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BioMed Central (BMC)
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Use of satellite data for atmospheric pollution and greenhouse gas monitoring. A contribution to ACCENT-TROPOSAT-2, task group 3. ACCENT reports, 1.2007
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Use of three-dimensional (3D) tissue equivalents in toxicology has been increasing over the last decade as novel preclinical test systems and as alternatives to animal testing. In the area of genetic toxicology, progress has been made with establishing robust protocols for skin, airway (lung) and liver tissue equivalents. In light of these advancements, a “Use of 3D Tissues in Genotoxicity Testing” working group (WG) met at the 7th IWGT meeting in Tokyo in November 2017 to discuss progress with these models and how they may fit into a genotoxicity testing strategy. The workshop demonstrated that skin models have reached an advanced state of validation following over 10 years of development, while liver and airway model-based genotoxicity assays show promise but are at an early stage of development. Further effort in liver and airway model-based assays is needed to address the lack of coverage of the three main endpoints of genotoxicity (mutagenicity, clastogenicity and aneugenicity), and information on metabolic competence. The IWGT WG believes that the 3D skin comet and micronucleus assays are now sufficiently validated to undergo an independent peer review of the validation study, followed by development of individual OECD Test Guidelines.
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