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TK-4103C/D Mongstad. Spredningsberegninger. NILU OR
NILU - Norsk institutt for luftforskning har på oppdrag fra Statoil Petroleum gjort spredningsberegninger av utslipp av SO2 til luft fra skorstein TK-4103C/D på Mongstad.
Beregningene gjøres som forarbeid i forbindelse med planlagte arbeider og oppgraderinger ved raffineriet (modifikasjon M1: 42647634 ¿ avgassutfordringer fra SRU RS14). Resultatene sammenlignes med gjeldende akseptkriterier, deriblant ACGIH TLV-STEL (American Conference of Governmental Industrial Hygiene som har korttids grenseverdi lik 0,65 mg/m3). Konklusjonen er at de fleste beregningspunktene viser høyere maksimumskonsentrasjon enn ACGIH-standarden. Forslag til avbøtende tiltak og mulige forholdsregler er gitt.
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Titanium dioxide nanoparticles (TiO2 NPs) are used in a wide range of applications. Although inhalation of NPs is one of the most important toxicologically relevant routes, experimental studies on potential harmful effects of TiO2 NPs using a whole-body inhalation chamber model are rare. In this study, the profile of lymphocyte markers, functional immunoassays, and antioxidant defense markers were analyzed to evaluate the potential adverse effects of seven-week inhalation exposure to two different concentrations of TiO2 NPs (0.00167 and 0.1308 mg TiO2/m3) in mice. A dose-dependent effect of TiO2 NPs on innate immunity was evident in the form of stimulated phagocytic activity of monocytes in low-dose mice and suppressed secretory function of monocytes (IL-18) in high-dose animals. The effect of TiO2 NPs on adaptive immunity, manifested in the spleen by a decrease in the percentage of T-cells, a reduction in T-helper cells, and a dose-dependent decrease in lymphocyte cytokine production, may indicate immunosuppression in exposed mice. The dose-dependent increase in GSH concentration and GSH/GSSG ratio in whole blood demonstrated stimulated antioxidant defense against oxidative stress induced by TiO2 NP exposure.
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