Gå til innhold
  • Send

  • Kategori

  • Sorter etter

  • Antall per side

Fant 9885 publikasjoner. Viser side 346 av 396:

Publikasjon  
År  
Kategori

The colony forming efficiency assay for toxicity testing of nanomaterials—Modifications for higher-throughput

Rundén-Pran, Elise; Mariussen, Espen; El Yamani, Naouale; Elje, Elisabeth; Longhin, Eleonora Marta; Dusinska, Maria

To cope with the high number of nanomaterials manufactured, it is essential to develop high-throughput methods for in vitro toxicity screening. At the same time, the issue with interference of the nanomaterial (NM) with the read-out or the reagent of the assay needs to be addressed to avoid biased results. Thus, validated label-free methods are urgently needed for hazard identification of NMs to avoid unintended adverse effects on human health. The colony forming efficiency (CFE) assay is a label- and interference-free method for quantification of cytotoxicity by cell survival and colony forming efficiency by CFE formation. The CFE has shown to be compatible with toxicity testing of NMs. Here we present an optimized protocol for a higher-throughput set up.

Frontiers Media S.A.

2022

The comet assay applied to cells of the eye

Azqueta, Amaya; Rundén-Pran, Elise; Elje, Elisabeth; Nicolaissen, Bjørn; Haug, Kristiane; Smeringaiova, Ingrida; Jirsova, Katerina; Collins, Andrew Richard

Oxford University Press

2018

The comet assay applied to HepG2 liver spheroids

Elje, Elisabeth; Hesler, Michelle; Rundén-Pran, Elise; Mann, Pascal; Mariussen, Espen; Wagner, Sylvia; Dusinska, Maria; Kohl, Yvonne

2019

The comet assay as a tool for human biomonitoring studies: The ComNet Project.

Collins, A.; Koppen, G.; Valdiglesias, V.; Dusinska, M.; Kruszewski, M.; Møller, P.; Rojas, E.; Dhawan, A.; Benzie, I.; Coskun, E.; Moretti, M.; Speit, G.; Bonassi, S. for the ComNet project.

2014

The comet assay in animal models: From bugs to whales – (Part 1 Invertebrates)

Gajski, Goran; Žegura, Bojana; Ladeira, Carina; Pourrut, Bertrand; Del Bo, Cristian; Novak, Matjaž; Srámková, Monika; Milić, Mirta; Gutzkow, Kristine Bjerve; Costa, Solange; Dusinska, Maria; Brunborg, Gunnar; Collins, Andrew Richard

Elsevier

2019

The comet assay in animal models: From bugs to whales ? (Part 2 Vertebrates)

Gajski, Goran; Žegura, Bojana; Ladeira, Carina; Novak, Matjaž; Srámková, Monika; Pourrut, Bertrand; Del Bo', Cristian; Milić, Mirta; Gutzkow, Kristine Bjerve; Costa, Solange; Dusinska, Maria; Brunborg, Gunnar; Collins, Andrew Richard

Elsevier

2019

The comet assay in human biomonitoring: Technical and epidemiological perspectives

Collins, Andrew; Milic, Mirta; Bonassi, Stefano; Dusinska, Maria

2019

The Community Inversion Framework v1.0: a unified system for atmospheric inversion studies

Berchet, Antoine; Sollum, Espen; Thompson, Rona Louise; Pison, Isabelle; Thanwerdas, Joel; Broquet, Grégoire; Chevallier, Frédéric; Aalto, Tuula; Berchet, Adrien; Bergamaschi, Peter; Brunner, Dominik; Engelen, Richard; Fortems-Cheiney, Audrey; Gerbig, Christoph; Zwaaftink, Christine Groot; Haussaire, Jean-Matthieu; Henne, Stephan; Houweling, Sanne; Karstens, Ute; Kutsch, Werner L.; Luijkx, Ingrid T.; Monteil, Guillaume; Palmer, Paul I.; van Peet, Jacob C. A.; Peters, Wouter; Peylin, Philippe; Potier, Elise; Rödenbeck, Christian; Saunois, Marielle; Scholze, Marko; Tsuruta, Aki; Zhao, Yuanhong

2021

The concept of essential use for determining when uses of PFASs can be phased out

Cousins, Ian; Goldenman, G.; Herzke, Dorte; Lindstrom, A.; Lohmann, R.; Miller, M.; Ng, C. A.; Patton, S.; Scheringer, M.; Trier, X.; Wang, Z.; DeWitt, J. C.

2019

The concept of essential use for determining when uses of PFASs can be phased out

Cousins, Ian T.; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Miller, Mark; Ng, Carla A.; Patton, Sharyle; Scheringer, Martin; Trier, Xenia; Vierke, Lena; Wang, Zhanyun; DeWitt, Jamie

Royal Society of Chemistry (RSC)

2019

The consolidated European synthesis of CH4 and N2O emissions for the European Union and United Kingdom: 1990–2017

Petrescu, Ana Maria Roxana; Qiu, Chunjing; Ciais, Philippe; Thompson, Rona Louise; Peylin, Philippe; McGrath, Matthew J; Solazzo, Efisio; Janssens-Maenhout, Greet; Tubiello, Francesco N.; Bergamaschi, Peter; Brunner, Dominik; Peters, Glen Philip; Hoglund-Isaksson, Lena; Regnier, Pierre; Lauerwald, Ronny; Bastviken, David; Tsuruta, Aki; Winiwarter, Wilfried; Patra, Prabir K.; Kuhnert, Matthias; Oreggioni, Gabriel David; Crippa, Monica; Saunois, Marielle; Perugini, Lucia; Markkanen, Tiina; Aalto, Tuula; Zwaaftink, Christine Groot; Yao, Yuanzhi; Wilson, Chris; Conchedda, Giulia; Günther, Dirk; Leip, Adrian; Smith, Pete; Haussaire, Jean-Matthieu; Leppänen, Antti; Manning, Alistair J.; McNorton, Joe; Brockmann, Patrick; Dolman, Albertus Johannes

2021

The consolidated European synthesis of CH4 and N2O emissions for the European Union and United Kingdom: 1990–2019

Petrescu, Ana Maria Roxana; Qiu, Chunjing; McGrath, Matthew J; Peylin, Philippe; Peters, Glen Philip; Ciais, Philippe; Thompson, Rona Louise; Tsuruta, Aki; Brunner, Dominik; Kuhnert, Matthias; Matthews, Bradley; Palmer, Paul I.; Tarasova, Oksana; Regnier, Pierre; Lauerwald, Ronny; Bastviken, David; Hoglund-Isaksson, Lena; Winiwarter, Wilfried; Etiope, Giuseppe; Aalto, Tuula; Balsamo, Gianpaolo; Bastrikov, Vladislav; Berchet, Antoine; Brockmann, Patrick; Ciotoli, Giancarlo; Conchedda, Giulia; Monica, Crippa; Dentener, Frank; Zwaaftink, Christine Groot; Guizzardi, Diego; Günther, Dirk; Haussaire, Jean-Matthieu; Houweling, Sander; Janssens-Maenhout, Greet; Kouyate, Massaer; Leip, Adrian; Leppänen, Antti; Lugato, Emanuele; Maisonnier, Manon; Manning, Alistair J.; Markkanen, Tiina; McNorton, Joe; Muntean, Marilena; Oreggioni, Gabriel David; Patra, Prabir K.; Perugini, Lucia; Pison, Isabelle; Raivonen, Maarit T.; Saunois, Marielle; Segers, Arjo J.S.; Smith, Pete; Solazzo, Efisio; Tian, Hanqin; Tubiello, Francesco N. ; Vesala, Timo; Van Der Werf, Guido R. ; Wilson, Chris; Zaehle, Sönke

Knowledge of the spatial distribution of the fluxes of greenhouse gases (GHGs) and their temporal variability as well as flux attribution to natural and anthropogenic processes is essential to monitoring the progress in mitigating anthropogenic emissions under the Paris Agreement and to inform its global stocktake. This study provides a consolidated synthesis of CH4 and N2O emissions using bottom-up (BU) and top-down (TD) approaches for the European Union and UK (EU27 + UK) and updates earlier syntheses (Petrescu et al., 2020, 2021). The work integrates updated emission inventory data, process-based model results, data-driven sector model results and inverse modeling estimates, and it extends the previous period of 1990–2017 to 2019. BU and TD products are compared with European national greenhouse gas inventories (NGHGIs) reported by parties under the United Nations Framework Convention on Climate Change (UNFCCC) in 2021. Uncertainties in NGHGIs, as reported to the UNFCCC by the EU and its member states, are also included in the synthesis. Variations in estimates produced with other methods, such as atmospheric inversion models (TD) or spatially disaggregated inventory datasets (BU), arise from diverse sources including within-model uncertainty related to parameterization as well as structural differences between models. By comparing NGHGIs with other approaches, the activities included are a key source of bias between estimates, e.g., anthropogenic and natural fluxes, which in atmospheric inversions are sensitive to the prior geospatial distribution of emissions. ...

2023

The consolidated European synthesis of CO2 emissions and removals for the European Union and United Kingdom: 1990–2018

Petrescu, Ana Maria Roxana; McGrath, Matthew J; Andrew, Robbie; Peylin, Philippe; Peters, Glen Philip; Ciais, Philippe; Broquet, Grégoire; Tubiello, Francesco N.; Gerbig, Christoph; Pongratz, Julia; Janssens-Maenhout, Greet; Grassi, Giacomo; Nabuurs, Gert-Jan; Regnier, Pierre; Lauerwald, Ronny; Kuhnert, Matthias; Balkovic, Juraj; Schelhaas, Mart-Jan; van der Gon, Hugo A.C. Denier; Solazzo, Efisio; Qiu, Chunjing; Pilli, Roberto; Konovalov, Igor B.; Houghton, Richard A.; Günther, Dirk; Perugini, Lucia; Crippa, Monica; Ganzenmüller, Raphael; Luijkx, Ingrid T.; Smith, Pete; Munassar, Saqr; Thompson, Rona Louise; Conchedda, Giulia; Monteil, Guillaume; Scholze, Marko; Karstens, Ute; Brockmann, Patrick; Dolman, Albertus Johannes

2021

Publikasjon
År
Kategori