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Bhas 42 cell transformation assay for genotoxic and non-genotoxic carcinogens. Methods in Pharmacology and Toxicology
2014
Background
Prioritisation of chemical pollutants is a major challenge for environmental managers and decision-makers alike, which is essential to help focus the limited resources available for monitoring and mitigation actions on the most relevant chemicals. This study extends the original NORMAN prioritisation scheme beyond target chemicals, presenting the integration of semi-quantitative data from retrospective suspect screening and expansion of existing exposure and risk indicators. The scheme utilises data retrieved automatically from the NORMAN Database System (NDS), including candidate substances for prioritisation, target and suspect screening data, ecotoxicological effect data, physico-chemical data and other properties. Two complementary workflows using target and suspect screening monitoring data are applied to first group the substances into six action categories and then rank the substances using exposure, hazard and risk indicators. The results from the ‘target’ and ‘suspect screening’ workflows can then be combined as multiple lines of evidence to support decision-making on regulatory and research actions.
Results
As a proof-of-concept, the new scheme was applied to a combined dataset of target and suspect screening data. To this end, > 65,000 substances on the NDS, of which 2579 substances supported by target wastewater monitoring data, were retrospectively screened in 84 effluent wastewater samples, totalling > 11 million data points. The final prioritisation results identified 677 substances as high priority for further actions, 7455 as medium priority and 326 with potentially lower priority for actions. Among the remaining substances, ca. 37,000 substances should be considered of medium priority with uncertainty, while it was not possible to conclude for 19,000 substances due to insufficient information from target monitoring and uncertainty in the identification from suspect screening. A high degree of agreement was observed between the categories assigned via target analysis and suspect screening-based prioritisation. Suspect screening was a valuable complementary approach to target analysis, helping to prioritise thousands of substances that are insufficiently investigated in current monitoring programmes.
Conclusions
This updated prioritisation workflow responds to the increasing use of suspect screening techniques. It can be adapted to different environmental compartments and can support regulatory obligations, including the identification of specific pollutants in river basins and the marine environments, as well as the confirmation of environmental occurrence levels predicted by modelling tools.
2024
Urban nature-based solutions (NBS) are increasingly deployed to restore ecosystems, regulate microclimates, support biodiversity, and enhance wellbeing. Yet many remain short-lived: once installation and early monitoring end, maintenance budgets shrink, responsibilities become unclear, and socio–ecological performance declines. The EU BiodivNBS NatureScape project addresses this overlooked post-implementation phase by examining how NBS are cared for, governed, and experienced over time in seven European cities – Oslo, Dublin, Riga, Milan, Lisbon, Lublin, and St. Gallen.To strengthen long-term sustainability, NatureScape establishes Transformation Labs (T-Labs) at demonstration sites, including rain gardens in Lublin; community gardens in Oslo, Riga, Milan, and St. Gallen; school gardens in Lisbon; and goat-grazing vegetation management in Dublin. These T-Labs function as practice-based innovation spaces where municipal authorities, researchers, and community groups jointly observe socio–ecological dynamics, identify stewardship challenges, and co-develop adaptive responses. The approach extends conventional living labs by focusing on long-term socio–ecological change and governance arrangements that support NBS persistence.NatureScape integrates baseline assessments across five forms of capital (natural, social, human, manufactured, financial) with participatory workshops, PPGIS, citizen science, and systems tools such as causal loop diagrams and multi-criteria assessments. This mixed-methods design enables analysis of NBS as dynamic systems shaped by interactions between ecological conditions, institutions, and community practices.Early findings from Oslo, Riga, Lublin and St. Gallen reveal recurrent barriers: unclear responsibilities after project funding ends, limited resources for routine care and climate adaptation, insecure land tenure, weak alignment with municipal strategies, and uneven community participation. In St. Gallen, expectations to expand activities, actors, or spatial scope further increase complexity and demand stronger management capacities.This study presents the NatureScape framework for post-implementation NBS governance and demonstrates how T-Labs can: (i) shift perceptions of NBS from temporary projects to living infrastructures requiring continuous care; (ii) clarify and redistribute responsibilities and resources for long-term stewardship; and (iii) provide structured settings where new forms of cooperation and valuation can be tested and embedded in policy. Embedding co-maintenance and co-stewardship as core practices can help cities move beyond pilot projects toward durable, multifunctional NBS aligned with EU and global biodiversity frameworks and targets.
2026
2002
2000
Betydningen av den nordatlantiske svingning (NAO) for sjøsaltepisoder og forsuring i vassdrag på Vestlandet og i Trøndelag. NIVA rapport, 4592-2002
2002
2011
Bestemmelse av dissosiasjon av gadolinium fra organiske gadoliniumforbindelser i sjøvann. Sluttrapport. NILU rapport
2017
Best practices for local and regional air quality management. Version 1.
FAIRMODE is the Forum for Air Quality Modeling created for exchanging experience and results from air quality modeling in the context of the Air Quality Directives (AQD) and for promoting the use of modeling for air quality assessment and management. FAIRMODE is organized in different activities and task, called cross-cutting tasks, to which representative of Member States and experts participate. Among the different activities, one is devoted to Air Quality management practices, called cross-cutting task 5 (CT5). This report is indeed based on the last activities of the FAIRMODE Cross Cutting Task 5 (CT5), focusing, in particular, on elaborating recommendations to support local, regional and national authorities in the use of modelling for the development of air quality plans, defining on how to quantify emission changes associated to a set of measures, and quantifying their impacts in terms of concentration (using an ‘impact pathway approach’ from ‘abatement measure’ to ‘emissions’ to ‘concentrations’). This is done on one side taking advantage of the results already produced by previous FAIRMODE working groups and in coordination with existing activities under other FAIRMODE CTs. On the other side, examples of best practice policies are presented, focusing on Low emission zones: with an example on Antwerp and Copenhagen, Measures on non-exhaust traffic to reduce PM, with an application on Stockholm. How to reduce ozone concentrations, with a focus on local to global contributions. How to build an air quality plan in an integrated way, with an application on Italy. How to evaluate the socio-economic impact of measures, focusing on a case study on UK. The results show how different pollutants should be tackled differently, the importance of integration among different sectoral plans (on emissions, greenhouse gases mitigation, …) and also how other dimensions of the problem (i.e. social aspects) should be considered when building air quality plans.
Publications Office for the European Union
2022
Best Practice Protocol for the validation of Aerosol, Cloud, and Precipitation Profiles (ACPPV)
Committee on Earth Observation Satellites - CEOS
2025
Beskrivelse og vurdering av forurensning fra kilder utenfor norsk del av Barentshavet. Akvaplan-niva Rapport, APN-421.2871
2003
Beskrivelse av nødvendig funksjonalitet for å bruke måledelen av AirQUIS til samplede prøver. NILU TR
2005
2007
2008
Beregning av maksimalkonsentrasjon av nitrogenoksider for utslipp fra raffineriet på Slagentangen. NILU OR
2007