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Nanomaterial grouping: Existing approaches and future recommendations

Giusti, Anna; Atluri, Rambabu; Tsekovska, Rositsa; Gajewicz, Agnieszka; Apostolova, Margarita; Battistelli, Chiara L.; Bleeker, Eric; Bossa, Cecilia; Bouillard, Jaques; Dusinska, Maria; Gómez-Fernández, Paloma; Grafström, Roland; Gromelski, Maciej; Handzhiyski, Yordan; Jacobsen, Nicklas Raun; Jantunen, Paula; Jensen, Keld Alstrup; Mech, Agnieszka; Navas, José Maria; Nymark, Penny; Oomen, Agnes G.; Puzyn, Tomasz; Rasmussen, Kirsten; Riebeling, Christian; Rodriguez-LLopis, Isabel; Sabella, Stefania; Sintes, Juan Riego; Suarez-Merino, Blanca; Tanasescu, Speranta; Wallin, Håkan; Haase, Andrea

The physico-chemical properties of manufactured nanomaterials (NMs) can be fine-tuned to obtain different functionalities addressing the needs of specific industrial applications. The physico-chemical properties of NMs also drive their biological interactions. Accordingly, each NM requires an adequate physico-chemical characterization and potentially an extensive and time-consuming (eco)toxicological assessment, depending on regulatory requirements. Grouping and read-across approaches, which have already been established for chemicals in general, are based on similarity between substances and can be used to fill data gaps without performing additional testing. Available data on “source” chemicals are thus used to predict the fate, toxicokinetics and/or (eco)toxicity of structurally similar “target” chemical(s). For NMs similar approaches are only beginning to emerge and several challenges remain, including the identification of the most relevant physico-chemical properties for supporting the claim of similarity. In general, NMs require additional parameters for a proper physico-chemical description. Furthermore, some parameters change during a NM's life cycle, suggesting that also the toxicological profile may change.

This paper compares existing concepts for NM grouping, considering their underlying basic principles and criteria as well as their applicability for regulatory and other purposes. Perspectives and recommendations based on experiences obtained during the EU Horizon 2020 project NanoReg2 are presented. These include, for instance, the importance of harmonized data storage systems, the application of harmonized scoring systems for comparing biological responses, and the use of high-throughput and other screening approaches. We also include references to other ongoing EU projects addressing some of these challenges.

Elsevier

2019

Zeppelinobservatoriet på Svalbard

Tørseth, Kjetil (intervjuobjekt); Andreassen, Rune Nordgård (journalist)

2019

Opinion of the Scientific Committee on Consumer safety (SCCS) – Opinion on the safety of cosmetic ingredient salicylic acid (CAS 69-72-7)

Bernauer, Ulrike; Bodin, Laurent; Chaudhry, Qasim; Coenraads, Pieter; Dusinska, Maria; Ezendam, Janine; Gaffet, E.; Galli, Corrado Lodovico; Granum, Berit; Panteri, E.; Rogiers, V.; Rousselle, C; Stepnik, Maciej; Vanhaecke, T.; Wijnhoven, S.

Elsevier

2019

Lufta er for alle!

Grossberndt, Sonja; Castell, Nuria; Gray, Laura

2019

The relationship between per- and polyfluoroalkyl substances (PFASs), persistent organic pollutants (POPs) and trace elements and thyroid hormone status in glaucous gulls (Larus hyperboreus)

Mortensen, Åse-Karen; Hovden, T. S.; Ciesielski, Tomasz Maciej; Heimstad, Eldbjørg Sofie; Gabrielsen, Geir W.; Jenssen, Bjørn Munro

2019

Innovative environmental monitoring for Norwegian municipalities using low-cost sensor networks. The iFLINK project.

Castell, Nuria; Dauge, Franck Rene; Grossberndt, Sonja; Høiskar, Britt Ann Kåstad; Lahoz, William A.; Lepioufle, Jean-Marie; Logna, Robert; Schneider, Philipp; Vallejo, Islen; Vogt, Matthias; Bartonova, Alena

2019

Europe's urban air quality — re-assessing implementation challenges in cities

Öztürk, Evrim Dogan; Lükewille, Anke; Ortiz, Alberto González; Viana, Mar; Bartonova, Alena; Guerreiro, Cristina D.b.b.; de Leeuw, Frank

This report analyses the implementation of EU air quality legislation at the urban level and identifies some of the reasons behind persistent air quality problems in Europe's cities. It is produced in cooperation with 10 cities involved in a 2013 Air Implementation Pilot project: Antwerp (Belgium), Berlin (Germany), Dublin (Ireland), Madrid (Spain), Malmö (Sweden), Milan (Italy), Paris (France), Plovdiv (Bulgaria), Prague (Czechia) and Vienna (Austria).

European Environment Agency

2019

Year-Round In Situ Measurements of Arctic Low-Level Clouds: Microphysical Properties and Their Relationships With Aerosols

Koike, Makoto; Ukita, Jinro; Ström, Johan; Tunved, Peter; Shiobara, Masataka; Vitale, Vito; Lupi, Angelo; Baumgardner, D.; Ritter, Christoph; Hermansen, Ove; Yamada, K.; Pedersen, Christina Alsvik

Two years of continuous in situ measurements of Arctic low‐level clouds have been made at the Mount Zeppelin Observatory (78°56′N, 11°53′E), in Ny‐Ålesund, Spitsbergen. The monthly median value of the cloud particle number concentration (Nc) showed a clear seasonal variation: Its maximum appeared in May–July (65 ± 8 cm−3), and it remained low between October and March (8 ± 7 cm−3). At temperatures warmer than 0 °C, a clear correlation was found between the hourly Nc values and the number concentrations of aerosols with dry diameters larger than 70 nm (N70), which are proxies for cloud condensation nuclei (CCN). When clouds were detected at temperatures colder than 0 °C, some of the data followed the summertime Nc to N70 relationship, while other data showed systematically lower Nc values. The lidar‐derived depolarization ratios suggested that the former (CCN‐controlled) and latter (CCN‐uncontrolled) data generally corresponded to clouds consisting of supercooled water droplets and those containing ice particles, respectively. The CCN‐controlled data persistently appeared throughout the year at Zeppelin. The aerosol‐cloud interaction index (ACI = dlnNc/(3dlnN70)) for the CCN‐controlled data showed high sensitivities to aerosols both in the summer (clean air) and winter–spring (Arctic haze) seasons (0.22 ± 0.03 and 0.25 ± 0.02, respectively). The air parcel model calculations generally reproduced these values. The threshold diameters of aerosol activation (Dact), which account for the Nc of the CCN‐controlled data, were as low as 30–50 nm when N70 was less than 30 cm−3, suggesting that new particle formation can affect Arctic cloud microphysics.

American Geophysical Union (AGU)

2019

Low-cost air quality sensors and their use for urban-scale modelling

Schneider, Philipp; Liu, Hai-Ying; Castell, Nuria; Hamer, Paul David; Vogt, Matthias; Dauge, Franck Rene; Bartonova, Alena

2019

The Atmosphere Above Ny-Ålesund: Climate and Global Warming, Ozone and Surface UV Radiation

Maturilli, Marion; Hanssen-Bauer, Inger; Neuber, Roland; Rex, Markus; Edvardsen, Kåre

2019

Ozonlaget - den internasjonale ozondagen

Hansen, Georg Heinrich (intervjuobjekt)

2019

Scenario calculations of mercury exposure from fish and overview of species with high mercury concentrations. Opinion of the Panel on Contaminants of the Norwegian Scientific Committee for Food and Environment

Amlund, Heidi; Rakkestad, Kirsten Eline; Ruus, Anders; Starrfelt, Jostein; Beyer, Jonny; Brantsæter, Anne Lise; Bremer, Sara; Eriksen, Gunnar Sundstøl; Mariussen, Espen; Samdal, Ingunn Anita; Thomsen, Cathrine; Knutsen, Helle Katrine

Norwegian Scientific Committee for Food and Environment (VKM)

2019

Vurdering av rentbrennende vedovners betydning for partikkelutslipp i Oslo kommune. Effekt på svevestøvnivåer.

Lopez-Aparicio, Susana; Grythe, Henrik

Målet med studien er å vurdere effekten av tilskudd til utskifting av gamle vedovner til nye rentbrennende ovner, og i hvilken grad ordningen har påvirket det totale partikkelutslippet og luftkonsentrasjoner i Oslo kommune. NILU har utført tre beregninger; 1) utslippsmodellering og spredningsberegninger for 4 ulike scenarioer; 2) utslippsreduksjon fra tilskuddsordningen i Oslo kommune; og 3) vurdering av tidsutvikling av vedfyringsutslipp, vedforbruk og utslippsfaktorer for kommuner med og uten tilskuddsordning. Modellering og vurdering av den potensielle utslippsreduksjonen som kan tilskrives tilskuddsordningen, viser at tilskuddsordningen potensielt har en stor effekt på reduksjon av partikkelutslipp og konsentrasjoner av PM2.5 og PM10. Beregnigene viser at tilskuddsordningen i Oslo kommune gir betydelig redusert utslippsfaktor over tid, men effekten på totalt PM-utslipp er liten.

NILU

2019

Electrochemical Behaviour of Carbon Anodes Produced with Different Mixing Temperatures and Baking Levels—A Laboratory Study

Sommerseth, Camilla; Thorne, Rebecca Jayne; Gebarowski, Wojciech; Ratvik, Arne Petter; Rørvik, Stein; Linga, Hogne; Lossius, Lorentz Petter; Svensson, Ann Mari

2019

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