Publikasjoner

High levels of ultraviolet radiation observed by ground-based instruments below the 2011 Arctic ozone hole.

Bernhard, G.; Dahlback, A.; Fioletov, V.; Heikkilä, A.; Johnsen, B.; Koskela, T.; Lakkala, K.; Svendby, T.

High levels of emerging and legacy contaminants in whales from Norway

Andvik, Clare Margaret; Jourdain, Eve Marie; Lyche, Jan Ludvig; Enge, Ellen Katrin; Harju, Mikael; Haug, Tore; Karoliussen, Richard; Borgå, Katrine

High levels of DDT in breast milk: Intake, risk, lactation duration, and involvement of gender.

Bouwman, H.; Kylin, H.; Seredad, B.; Bornmane, R.

High Arctic UV radiation levels in the spring of 2011 caused by unprecedented chemical ozone loss. NILU PP

Bernhard, G.; Fioletov, V.; Heikkilä, A.; Johnsen, B.; Koskela, T.; Lakkala, K.; Myhre, C.L.

Hierarchical Clustering and Dissimilarity Polygon Analyses. Optimizing the Polish Deposition Network.

Soares, Joana; Aas, Wenche; Eckhardt, Sabine; Guerreiro, Cristina

The potential re-design of the current deposition monitoring network in Poland was assessed by hierarchical clustering analysis. This statistical method determines the inherent or natural groupings of datasets, and/or to provide a summarization of data into groups using different metrics to assess the (di)similarity. The metrics are based on the correlation, to assess the temporal similarity, the Euclidean distance, to assess the magnitude similarity, and the combination of both. This method was used to assess the areas with similar deposition patters across the country based on measurement and model data for acidic compounds and heavy metals. The analysis clearly identified stations potentially redundant or measuring unique deposition patters and regions that represent the potential location of a single station.

NILU

HFC-43-10mee atmospheric abundances and global emission estimates.

Arnold, T.; Ivy, D.J.; Harth, C.M.; Vollmer, M.K.; Muhle, J.; Salameh, P.K.; Steele, L.P.; Krummel, P.B.; Wang, R.H.J.; Young, D.; Lunder, C.R.; Hermansen, O.; Rhee, T.S.; Kim, J.; Reimann, S.; O'Doherty, S.; Fraser, P.J.; Simmonds, P.G.; Prinn, R.G.; Weiss, R.F.

Hexachlorocyclohexanes in the Canadian Archipelago. 1. Spatial distribution and pathways of alpha-, beta-, and gamma-HCHs in surface water.

Bidleman, T.F.; Kylin, H.; Jantunen, L.M.; Helm, P.A.; Macdonald, R.W.

Heterogeneous nucleation on rough surfaces: implications to atmospheric aerosols.

Lazaridis, M.; Hov, Ø.; Eleftheriadis, K.

Her fyrer vi mest og minst med ved

Grythe, Henrik (intervjuobjekt); Leine, Jan Erlend (journalist)

Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model

Elje, Elisabeth; Mariussen, Espen; Moriones, Oscar H.; Bastus, Neus G.; Puntes, Victor; Kohl, Yvonne; Dusinska, Maria; Rundén-Pran, Elise

(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures. This study aims to compare cytotoxic and genotoxic responses induced by titanium dioxide (TiO2), silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs) in 2D monolayer and 3D spheroid cultures of HepG2 human liver cells. (2) NPs were characterized by electron microscopy, dynamic light scattering, laser Doppler anemometry, UV-vis spectroscopy and mass spectrometry. Cytotoxicity was investigated by the alamarBlue assay and confocal microscopy in HepG2 monolayer and spheroid cultures after 24 h of NP exposure. DNA damage (strand breaks and oxidized base lesions) was measured by the comet assay. (3) Ag-NPs were aggregated at 24 h, and a substantial part of the ZnO-NPs was dissolved in culture medium. Ag-NPs induced stronger cytotoxicity in 2D cultures (EC50 3.8 µg/cm2) than in 3D cultures (EC50 > 30 µg/cm2), and ZnO-NPs induced cytotoxicity to a similar extent in both models (EC50 10.1–16.2 µg/cm2). Ag- and ZnO-NPs showed a concentration-dependent genotoxic effect, but the effect was not statistically significant. TiO2-NPs showed no toxicity (EC50 > 75 µg/cm2). (4) This study shows that the HepG2 spheroid model is a promising advanced in vitro model for toxicity assessment of NPs.

MDPI

HENVINET. Second annual review of research and best practice. NILU OR

Yang, A.; Bartonova, A. (eds.)

The aim of this report is to present an overview of the framework for assessment of knowledge quality and identification of knowledge gaps within the HENVINET project. The focus is on four priority health end points as defined in the European Health Action Plan (EHAP); asthma and allergies, cancer, neurodevelopmental disorders and endocrine disruptors. This report is structured into two parts, where Part A introduces the HENVINET methodology, and Part B gives an example of how it is implemented through the different steps. The available results are furthermore presented in the Annexes.

HENVINET. Report on raising public participation and awareness and report from final project meeting. NILU OR

Hazel, P. van den, Liu, H.-Y.; Bartonova, A.; Grossberndt, S. (eds.) .

The aim of this report is to describe the ways to raise public participation and awareness of environmental health issues. It includes: (1) science-policy communications and stakeholder engagement; (2) network portal; (3) knowledge evaluation on hot topics within environmental health fields; and (4) decision support tools for practitioners. In addition, this report summarizes the main outcome from the HENVINET final conference. It includes: (1) complexity in environment and health; (2) tools for practice; (3) communication strategies; and (4) exchange of knowledge and results with related projects and research initiatives.