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Fant 10464 publikasjoner. Viser side 17 av 419:

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Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)

Pfuhler, Stefan; Benthem, Jan van; Curren, Rodger; Doak, Shareen H.; Dusinska, Maria; Hayashi, Makoto; Heflich, Robert H.; Kidd, Darren; Kirkland, David; Luan, Yang; Ouedraogo, Gladys; Reisinger, Kerstin; Sofuni, Toshio; Acker, Frederique van; Yang, Ying; Corvi, Raffaella

Use of three-dimensional (3D) tissue equivalents in toxicology has been increasing over the last decade as novel preclinical test systems and as alternatives to animal testing. In the area of genetic toxicology, progress has been made with establishing robust protocols for skin, airway (lung) and liver tissue equivalents. In light of these advancements, a “Use of 3D Tissues in Genotoxicity Testing” working group (WG) met at the 7th IWGT meeting in Tokyo in November 2017 to discuss progress with these models and how they may fit into a genotoxicity testing strategy. The workshop demonstrated that skin models have reached an advanced state of validation following over 10 years of development, while liver and airway model-based genotoxicity assays show promise but are at an early stage of development. Further effort in liver and airway model-based assays is needed to address the lack of coverage of the three main endpoints of genotoxicity (mutagenicity, clastogenicity and aneugenicity), and information on metabolic competence. The IWGT WG believes that the 3D skin comet and micronucleus assays are now sufficiently validated to undergo an independent peer review of the validation study, followed by development of individual OECD Test Guidelines.

2020

Use of a Lagrangian transport model for atmospheric inversions using satellite observations: case study using TROPOMI to estimate CH4 emissions over Europe

Thompson, Rona Louise; Pisso, Ignacio; Schneider, Philipp; Stebel, Kerstin; Krishnankutty, Nalini; Platt, Stephen Matthew

2024

Usare gli oceani per catturare l'anidride carbonica? Una tecnologia ancora non matura

Muri, Helene (intervjuobjekt)

Per raggiungere gli obbiettivi climatici oggi bisogna dare priorità a metodi che sappiamo già essere efficaci e non creano danni ulteriori all'ambiente

2025

Urinary mercury in adults in Poland living near a chloralkali plant.

Jarosinska, D.; Barregård, L.; Biesiada, M.; Muszynska-Graca, M.; Dabkowska, B.; Denby, B.; Pacyna, J.; Fudala, J.; Zielonka, U.

2006

Urban Transformation to Carbon-Free with Lush Greenery and Colored Solar Energy and Storage Technologies at the Diverse Climatic Conditions of Europe

Karamanis, Dimitrios; Liu, Hai-Ying; Avisar, Dror; Braslina, Liga; Cabeza, Luisa F.; D'Agostino, Dominic; Kapsalis, Vasileios; Lapka, P.; Raita, O.; Skandalos, Nikolaos; Vanhuyse, F.

2024

Urban particulate matter: Technologies for assessment and need for information.

Bartonova, A.; Castell, N.; Dauge, F. R.; Grossberndt. S.; Schneider, P.

2017

Urban particulate matter: technologies for assessment and need for information

Bartonova, Alena; Castell, Nuria; Dauge, Franck Rene; Grossberndt, Sonja; Schneider, Philipp

2019

Urban NO2 and PM2.5 Air Quality Data Fusion Modelling: Integrating Citizen Science and Low-Cost Sensor Data with Dispersion Modelling

O'Regan, Anna C.; Grythe, Henrik; Hellebust, Stig; Lopez-Aparicio, Susana; O'Dowd, Colin; Hamer, Paul David; Schneider, Philipp; Santos, Gabriela Sousa; Nyhan, Marguerite M.

2026

Urban Living Labs for Healthy and People-Centered Cities: A Nordic Model

Steffansen, Rasmus Nedergård; Lissandrello, Enza; Castell, Nuria

2023

Urban Living Labs as Inter- and Transdisciplinary Arenas for Sustainability Planning Research

Steffansen, Rasmus Nedergård; Lissandrello, Enza; Castell, Nuria; Ekman, Karin; Watne, Ågot K.; Roux, Marta Segura

The transition towards sustainable societies necessitates inter- and transdisciplinary knowledge, particularly in urban planning, where diverse knowledge traditions are crucial for decision-making. Despite this, planning practices often remain entrenched in institutional and legal frameworks that hinder the integration of multiple ways of knowing and undervalue lay knowledge. Researcher-led urban innovation processes are increasingly adopting experimental approaches for the multi-stakeholder co-creation of knowledge, addressing urban challenges through interdisciplinary approaches. This article addresses the interdisciplinary collaboration between researchers in experimental urban planning processes by examining a research project that focused on participatory environmental co-monitoring and planning for urban air quality in Nordic contexts. The study builds a bridge between theories of interdisciplinarity, urban experimentation, and planning theory. By presenting urban living labs (ULLs) as arenas for co-learning that integrate scientific and lay knowledge, the article explores how planning researchers can facilitate mutual learning and navigate the micropolitics of knowledge co-production. We develop the concept of cross-disciplinary unknowns to highlight the dynamics and challenges in research teams with diverse epistemological backgrounds. We argue that an explicit and structured approach for explicating epistemological differences can facilitate the detection of unreflected knowledge retention between disciplines.

2026

Urban greenhouse gas emissions assessment: observations and modelling in a pilot study for the Oslo area.

Pisso, Ignacio; Lopez-Aparicio, Susana; Schneider, Philipp; Vogt, Matthias; Dauge, Franck Rene; Schmidbauer, Josef Norbert; Krognes, Terje

2018

Urban Exposure. Haifa case study. Powerpoint presentation. NILU F

Broday, D.; Mc Innes, H.; Fløisand, I.; Laupsa, H.

2005

Urban Exposure. Final report. NILU OR

Fløisand, I. (eds.) Bøhler, T. (coord.).

2006

Urban Exposure. Case studies for Oslo and Katowice. Powerpoint presentation. NILU F

Fudala, J.; Lützenkirchen, S.; Fløisand, I.

2005

Urban Exposure. Case studies for Oslo and Katowice. Powerpoint presentation. NILU F

Lützenkirchen, S.; Fudala, J.; Fløisand, I.; Laupsa, H.

2005

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