Fant 9758 publikasjoner. Viser side 107 av 391:
2004
2017
2005
2007
Processes affecting the long-range transport potential of selected brominated flame retardants. NILU PP
2004
2000
Vinca Institute of Nuclear Sciences
2019
Proceedings of AMAP Workshop on Sources, Emissions and Discharges. Kjeller, 23-24 August 2001. NILU OR
2002
2016
Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point sources can provide information about the processes governing uptake, distribution and elimination of PFASs. Median tissue/blood ratios (TBRs) were consistently <1 for all PFASs and tissues except bile which displayed a distinct distribution pattern and enrichment of several perfluoroalkyl sulfonic acids. Transformation of concentration data into relative body burdens (RBBs) demonstrated that blood, gonads, and muscle together accounted for >90% of the amount of PFASs in the organism. Principal component analyses of TBRs and RBBs showed that the functional group was a relatively more important predictor of internal distribution than chain-length for PFASs. Whole body bioaccumulation factors (BAFs) for short-chain PFASs deviated from the positive relationship with hydrophobicity observed for longer-chain homologues. Overall, our results suggest that TBR, RBB, and BAF patterns were most consistent with protein binding mechanisms although partitioning to phospholipids may contribute to the accumulation of long-chain PFASs in specific tissues.
2018
2023
2012
2009
2012
Prioritizing chemicals and data requirements for exposure and risk assessment. Poster presentation. NILU F
2010
Prioritization, screening and identification of organosilicon contaminants in the environment. NILU F
A mass balance model of chemical fate and bioaccumulation in the environment was used to rank 287 high- and low-production volume organosilicon compounds for their concentration in the environment and in top predators. Key physical chemical properties of each chemical were estimated using quantitative structure-activity relationships (QSARs) and a total emission estimate of each chemical was made using information, which included amounts entering commerce and emission factors. Based on the model predicted concentrations in air, sediment and human tissue, chemicals were selected for screening through environmental sampling and analysis. Known environmental organosilicon contaminants such as the cyclic and linear volatile methyl siloxanes (VMS) were excluded as well as structures subject to rapid hydrolysis, a feature which was not taken into account in the model simulations because of current limitations in predicting hydrolysis half-lives with QSARs. Analytical standards were only commercially available for half of the remaining 30 organosilicon compounds. Ten of these were not stable in solution, which left 5 organosilicon compounds eligible for environmental screening. These were tetrakis(trimethylsilyloxy)silane, phenyl-tris(trimethylsiloxy)silane, trifluoropropyltrimethylcyclotrisiloxane, trifluoropropylmethylcyclotetrasiloxane and tetraphenyltrisiloxane. Four of these chemicals were identified in sewage sludge, in sediment from Stockholm harbor, and in Stockholm ambient air samples. The trifluoropropyl-substituted siloxanes were analysed with UPLC-MS/MS, the others with GC-MS. Trifluoropropyltrimethylcyclotrisiloxane was solely detected as its corresponding linear diol. To date it is unclear whether the diol is present in the environment as such or formed during extraction or cleanup. The concentrations of the chemicals ranged from pg m-3 in air up to ng g-1 d.w. in sewage sludge, which are orders of magnitude below the levels of cyclic VMS (such as D5) in the same matrices.
2013
2024
2024
2004
2012